Shane Macedo
Senior Director • United States

Local Office:
12830 El Camino Real, Suite 100
San Diego, California 92130
United States
Office: +1 760 431 3820
Mobile: +1 619 717 9110
Shane Macedo
Senior Director • United States
About
Shane is a strategic commercial real estate advisor specializing in tenant representation, multi-market transactions, and global portfolio management. He has a proven track record of delivering data-driven real estate solutions, helping clients navigate complex lease negotiations, optimize corporate footprints, and improve operational efficiency.
Before joining Cushman & Wakefield, Shane spent nearly a decade at CBRE, where he managed high-value transactions and global real estate holdings for clients in the Healthcare, Life Sciences, and Medical Device sectors. His expertise spans global portfolio optimization, transaction execution management, process development and implementation, and overall strategic portfolio enhancement.
Prior to his career in corporate real estate, Shane served as a Lieutenant in the U.S. Navy, where he was a Surface Warfare Officer completing multiple overseas deployments aboard guided-missile destroyers. His military background instilled a disciplined, mission-driven approach to problem-solving and decision-making, which he applies to complex real estate strategies.
Clients
- Smith & Nephew, Global Portfolio – 11M SF
- Illumina, Global Portfolio – 4M SF
- Tandem Diabetes, Global Portfolio – 500K SF
- AMN Healthcare, National Portfolio – 350K SF
- LabCorp, Local Portfolio – 200K SF
Assignments
- Smith & Nephew – Memphis, TN – 210,000 SF
- Tandem Diabetes – San Diego, CA – 182,000 SF
- Smith & Nephew – Lawrenceville, GA – 115,000 SF
- AMN Healthcare – Dallas, TX – 95,000 SF
- Abzena – Carlsbad, CA – 85,000 SF
- LabCorp– San Diego, CA – 82,000 SF
- Illumina – San Diego, CA – 70,000 SF
Education
- Master of Business Administration (MBA), The College of William & Mary
- Bachelor of Business Administration (BBA), Marketing & Naval Science, University of San Diego