Why Choose St. Louis


St. Louis is a major city in Missouri with a thriving commercial real estate market that includes a variety of office leasing options.

17.3% Vacancy

$23.14Asking Rent,

St Louis Skyline

Latest Office Space Listings in St. Louis

Clayton - Office
Multiple Spaces


Shaw Park Plaza

1 N. Brentwood Blvd.
Clayton, MO 63105
United States

Total Available Space: 36,763 SF

Rental Price: $38.50 - $39.00 USD

Sappington - Office
Multiple Spaces


Laumeier Office Pk II

3636 S. Geyer Rd.
Sappington, MO 63127
United States

Total Available Space: 18,278 SF

Rental Price: $28.00 USD

Clayton - Office
Multiple Spaces


The Hoffmann Building

8000 Maryland Ave.
Clayton, MO 63105
United States

Total Available Space: 62,643 SF

Rental Price: $30.00 USD

Multiple Spaces


Innerbelt Center

2127 Innerbelt Business Center Dr.
St. Louis, MO 63114
United States

Total Available Space: 42,157 SF

Rental Price: $19.95 USD

Maryland Hts - Office



3251 Riverport Dr., #140
Maryland Hts, MO 63043
United States

Available Space: 10,522 SF

Rental Price: $22.50 USD

Multiple Spaces


Rock Spring School

3974 Sarpy Ave
St. Louis, Mo 63110
United States

Total Available Space: 15,268 SF

Rental Price: $27.00 USD

St. Louis - Office
Multiple Spaces


The Post

900 N Tucker
St. Louis, MO 63101
United States

Total Available Space: 149,364 SF

Rental Price: Negotiable

St. Louis - Office
Multiple Spaces


Paragon Building

12400 Olive Blvd.
St. Louis, MO 63141
United States

Total Available Space: 32,168 SF

Rental Price: $23.00 USD

Why implement your office in St. Louis? 

St. Louis is a major city in Missouri with a diverse and growing economy, making it an attractive location for businesses looking to lease office space. The city offers a range of office leasing options, from traditional high-rise buildings in downtown St. Louis to modern, flexible co-working spaces in trendy neighborhoods. Additionally, the cost of leasing office space in St. Louis is generally lower than in other major metropolitan areas, making it an appealing option for businesses looking to control costs. St. Louis also has a strong talent pool, with several universities and colleges in the area producing highly skilled graduates in various fields. As a result, the city is becoming an increasingly popular location for businesses across a variety of industries.

How much does it cost to rent an office in St. Louis?

The cost of renting an office in St. Louis can vary depending on several factors such as location, size, and amenities.

To read: our St. Louis MarketBeat Office report analyzes quarterly economic and commercial real estate activity including supply, demand and pricing trends at the market and submarket levels.

Are office space rents likely to increase in St. Louis?

The rental market in St. Louis is subject to change, but the city has seen steady growth in recent years. While rent increases can't be predicted with certainty, it's important to keep an eye on market trends when considering an office space for lease in St. Louis.

Popular neighborhoods in St. Louis?

St. Louis has several popular neighborhoods that offer unique amenities and environments, including:

  • Downtown: The heart of the city, downtown St. Louis is home to many of the city's major businesses, including law firms, financial institutions, and government offices. It's also a popular destination for entertainment and dining, with attractions such as Busch Stadium, the Gateway Arch, and several museums and theaters.
  • Central West End: Known for its charming tree-lined streets, upscale shops and restaurants, and historic homes, the Central West End is a popular neighborhood for young professionals and families. It's also home to several medical institutions, including Barnes-Jewish Hospital and Washington University School of Medicine.
  • The Loop: Located in the suburb of University City, the Loop is a vibrant entertainment district with a diverse mix of shops, restaurants, and music venues. It's also home to the historic Tivoli Theatre and the St. Louis Walk of Fame.
  • Clayton: Clayton is an affluent suburb of St. Louis that's home to several major corporations, including Enterprise Rent-A-Car and Centene Corporation. It's also known for its beautiful parks and trails, as well as its luxury shopping and dining options.
  • Soulard: One of the oldest neighborhoods in St. Louis, Soulard is known for its historic brick homes, vibrant nightlife, and the famous Soulard Farmers Market, which has been operating for over 200 years.

Getting to and from St. Louis?

St. Louis, located in the Midwestern United States, can be easily accessed by several transportation options.

  • By Air: The city is served by the Lambert-St. Louis International Airport (STL), which is located approximately 13 miles from downtown St. Louis. The airport is well-connected to several domestic and international destinations and offers ground transportation options such as rental cars, taxis, ride-sharing services, and public transportation.
  • By Car: St. Louis is located at the intersection of several major highways, including Interstate 70, Interstate 44, and Interstate 55. The city is also connected to several major cities in the Midwest by a network of interstate highways.
  • By Train: Amtrak offers train service to St. Louis via its Gateway Station, which is located in downtown St. Louis. The station is served by several routes, including the Missouri River Runner, which connects St. Louis to Kansas City, and the Texas Eagle, which connects St. Louis to Chicago and San Antonio.
  • By Bus: Several bus companies offer service to St. Louis, including Greyhound and Megabus. The city is also served by a local public transportation system, Metro Transit, which offers bus and light rail service throughout the region.

Commercial Real Estate Services in St. Louis, Missouri

 Our St. Louis team includes more than 1,400 professionals throughout the metro area. From the heart of Downtown to Chesterfield, Cushman & Wakefield will work with you to uncover innovative local and global real estate opportunities.
St. Louis Related Insights
St Louis Skyline

St. Louis

Cushman & Wakefield MarketBeat reports analyze quarterly economic and commercial real estate activity including supply, demand and pricing trends at the market and submarket levels.
Luke Partridge • 1/16/2024

U.S. Office Reports

Access the latest quarter commercial real estate results for the office sector nationally. MarketBeat analyzes quarterly market activity including supply, demand and pricing trends.
David Smith • 1/11/2024

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